Kaepernick will appear in the series and add his own voice to the project.
The limited series will run for six episodes and reunite DuVernay with Michael Starrbury, who will write and serve as executive producer.
DuVernay and Starrbury had already worked together on “When We See You,” which received 16 Emmy nominations.
In 2016, Kaepernick made national news when he refused to stand as the National Anthem played before NFL games. He said he did so to protest the police shootings of African-American men and other social injustices faced by blacks in the United States.
She added, “Colin’s story has a lot to say about identity, sports and the spirit of endurance and personal endurance. I couldn’t be happier to tell this story with the Netflix team.”
Netflix has also announced an official release date for the series.